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Oral minocin is indicated in the treatment of asymptomatic carriers of neisseria meningitidis to eliminate meningococci from the nasopharynx.

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Hypersensitivity reactionsUrticariaangioneurotic edemapolyarthralgiaanaphylaxis/anaphylactoid reactionincluding shock and fatalitiesanaphylactoid purpuramyocarditispericarditisexacerbation of systemic lupus erythematosus and pulmonary infiltrates with eosinophilia have been reportedA transient lupus-like syndrome and serum sickness-like reactions also have been reportedcytosishemolytic anemiathrombocytopenialeukopenianeutropeniapancytopeniaand eosinophilia have been reported.

8 years4 mg/kg PO/IV initiallynot to exceed 200 mgTHEN 2 mg/kg PO/IV q12hrnot to exceed adult dosenot to exceed 100 mg PO/IV q12hr for 5-10 days8 years4 mg/kg PO/IV initiallynot to exceed 200 mgTHEN 2 mg/kg PO/IV q12hrnot to exceed adult dosenot to exceed 100 mg PO/IV q12hr for 5-10 daysclasscalc_link

Intracranial hypertensionIHpseudotumor cerebrihas been associated with the use of tetracyclines including MinocinClinical manifestations of IH include headacheblurred visiondiplopiaand vision losspapilledema can be found on fundoscopyWomen of childbearing age who are overweight or have a history of IH are at greater risk for developing tetracycline associated IHConcomitant use of isotretinoin and Minocin should be avoided because isotretinoin is also known to cause pseudotumor cerebri.

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